Inner ear research data

Every result from your inner ear research, connected

exOtic is built to hold everything an inner ear study produces, from hearing tests and cochlear imaging today to transcriptomics and other omics as the platform grows. Each result is tied to its cohort, mouse, ear and timepoint the moment it's uploaded, which puts study- and cohort-level views, and analyses that cross-reference one kind of data against another, at your fingertips.

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A cohort matrix in exOtic: ABR thresholds for each mouse at baseline, 24 hours and 14 days after noise, shaded from better to worse, with the cohort mean
ABR thresholds for each mouse in a cohort, from baseline to 14 days after noise. Synthetic example data.

The problem

The data is there. The links between it aren't.

In most hearing labs, ABR files sit on one drive, confocal stacks on another, and the colony in a spreadsheet that only one person really understands. Which mouse was it, which ear, and how many days after noise? Too often the answer lives in a filename or in someone's memory. exOtic keeps those links for you, from the breeding cage to the published figure.

What exOtic does today

We started with the data most hearing labs collect first: functional recordings, cochlear imaging and the colony behind them.

Recordings

ABR and DPOAE, straight from the rig

Upload the files your rig already writes, TDT .arf and .awf included, and exOtic reads the mouse, ear and timepoint from your lab's own naming. ABR thresholds are called by ABRA, a published deep-learning model, Wave I amplitude and latency are tracked down every intensity series, and DPOAE thresholds come from the signal-to-noise ratio at each frequency.

One mouse's ABR recording in exOtic: its audiogram, and Wave I amplitude and latency by frequency
One recording: the audiogram, with Wave I amplitude and latency by frequency. Synthetic example data.
Imaging

Cochlear imaging, measured your lab's way

Confocal z-stacks open in the browser with orthogonal views and projections, so there's no export to Fiji just to take a look. Define once what your lab counts, whether ribbon synapses, hair cells or a stained area, and exOtic applies it to every image the same way, keeping each version of the definition so older counts stay traceable.

A confocal z-stack of cochlear hair cells open in the exOtic image viewer, with a channel per stain
A confocal z-stack in the viewer. Synthetic example data.
Colony

The colony spreadsheet you already keep

Bring in your colony as it stands, with its lines, cages, genotypes, parents and breeding pairs, whether it comes from colony management software or a layout of your own. Match your columns once and exOtic remembers them for every export after that.

The exOtic colony overview: mouse counts, the lab's lines with their genes, and breeding pairs with their status
The colony overview. Synthetic example data.
Studies

Cohorts on a schedule, per mouse

Set a study's timepoints once and each mouse runs on its own day 0. Cohort views show what's due, what's done and what's missing, with hearing and histology side by side, and the numbers export to CSV, Prism or NWB when it's time to write up.

Built with inner ear research labs

exOtic is made for auditory neuroscience and otology labs working in mouse models, from noise-induced and age-related hearing loss to ototoxicity and genetic studies. It's in use with partner labs today, and we're opening it to more.

Your lab's data stays your lab's: no other lab can see it, and nothing is shared without a signed agreement.

We'd like to hear about your study

If you run a hearing research lab and would like to see exOtic working with data like yours, send us a note and we'll set up a time to walk through it together.

rene.vielman@xoticdata.com